Maspin Antibody
Product Specifications
Background
SERPINB5 is a tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
NCBI Gene ID
5268
Swiss Prot
P36952
Accession Number
P36952
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This Maspin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-123 amino acids from the Central region of human Maspin.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
42 kDa
Fragment
Rabbit Ig
Symbol
SERPINB5
NCBI Official Name
Serpin B5
NCBI Organism
Homo sapiens
Background Reference 01
Kim, J., et al. Tumour Biol. 31 (5) :471-476 (2010)
Background Reference 02
Juengel, E., et al. WorldUrol 28 (4) :465-471 (2010)
Background Reference 03
Besgen, P., et al. J. Immunol. 184 (9) :5392-5402 (2010)
Background Reference 04
Fung, C.L., et al. Histopathology 56 (3) :319-330 (2010)
Other Product Names
Serpin B5, Maspin, Peptidase inhibitor 5, PI-5, SERPINB5, PI5
Tested Applications
WB, IHC-P, IF
Protein ID
229462757
Physical Properties
Liquid
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