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MET Antibody

Product Specifications

Background

The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

4233

Swiss Prot

P08581

Accession Number

P08581

Host

Rabbit

Reactivity

Human

Immunogen

This ZNF593 antibody is generated from rabbits immunized with a His fusion protein from human MET.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=56-218

Calculated Molecular Weight

156 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MET

NCBI Official Name

Hepatocyte growth factor receptor

NCBI Organism

Homo sapiens

Background Reference 01

Song, J., et al. Arch. Pathol. Lab. Med. 134 (11) :1702-1705 (2010)

Background Reference 02

Thanseem, I., et al. Neurosci. Res. 68 (2) :137-141 (2010)

Background Reference 03

Holgren, C., et al. Oncogene 29 (38) :5241-5253 (2010)

Background Reference 04

Sugiura, T., et al. Clin. Immunol. 136 (3) :387-399 (2010)

Other Product Names

Hepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met, MET

Tested Applications

WB

Protein ID

251757497

Physical Properties

Liquid

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