Tiparp Antibody
Product Specifications
Background
Tiparp is a poly [ADP-ribose] polymerase using NAD (+) as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor; repeated rounds of ADP-ribosylation leads to the formation of poly (ADPribose) chains on the protein, thereby altering the function of the target protein. May play a role in the adaptative response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals.
NCBI Gene ID
99929
Swiss Prot
Q8C1B2
Accession Number
Q8C1B2
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This Tiparp antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the C-terminal region of human Tiparp.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
76 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:500
Symbol
Tiparp
NCBI Official Name
TCDD-inducible poly [ADP-ribose] polymerase
NCBI Organism
Mus musculus
Background Reference 01
Schmahl, J., et al. Genes Dev. 22 (23) :3255-3267 (2008)
Background Reference 02
Schmahl, J., et al. Nat. Genet. 39 (1) :52-60 (2007)
Background Reference 03
Stryke, D., et al. Nucleic Acids Res. 31 (1) :278-281 (2003)
Background Reference 04
Ma, Q. Arch. Biochem. Biophys. 404 (2) :309-316 (2002)
Other Product Names
TCDD-inducible poly [ADP-ribose] polymerase, ADP-ribosyltransferase diphtheria toxin-like 14, ARTD14, Tiparp
Tested Applications
WB
Physical Properties
Liquid
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