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Tiparp Antibody

Product Specifications

Background

Tiparp is a poly [ADP-ribose] polymerase using NAD (+) as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor; repeated rounds of ADP-ribosylation leads to the formation of poly (ADPribose) chains on the protein, thereby altering the function of the target protein. May play a role in the adaptative response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals.

NCBI Gene ID

99929

Swiss Prot

Q8C1B2

Accession Number

Q8C1B2

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Tiparp antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the C-terminal region of human Tiparp.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=56-209

Calculated Molecular Weight

76 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:500

Symbol

Tiparp

NCBI Official Name

TCDD-inducible poly [ADP-ribose] polymerase

NCBI Organism

Mus musculus

Background Reference 01

Schmahl, J., et al. Genes Dev. 22 (23) :3255-3267 (2008)

Background Reference 02

Schmahl, J., et al. Nat. Genet. 39 (1) :52-60 (2007)

Background Reference 03

Stryke, D., et al. Nucleic Acids Res. 31 (1) :278-281 (2003)

Background Reference 04

Ma, Q. Arch. Biochem. Biophys. 404 (2) :309-316 (2002)

Other Product Names

TCDD-inducible poly [ADP-ribose] polymerase, ADP-ribosyltransferase diphtheria toxin-like 14, ARTD14, Tiparp

Tested Applications

WB

Physical Properties

Liquid

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