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SH2D4A Antibody

Product Specifications

Background

SH2D4A inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.

NCBI Gene ID

63898

Swiss Prot

Q9H788

Accession Number

Q9H788

Host

Rabbit

Reactivity

Human

Immunogen

This SH2D4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-67 amino acids from the N-terminal region of human SH2D4A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=56-202

Calculated Molecular Weight

53 kDa

Fragment

Rabbit Ig

Symbol

SH2D4A

NCBI Official Name

SH2 domain-containing protein 4A

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Li, T., et al. BMB Rep 42 (8) :516-522 (2009)

Background Reference 03

Venkatesan, K., et al. Nat. Methods 6 (1) :83-90 (2009)

Background Reference 04

Lapinski, P.E., et al. J. Immunol. 181 (3) :2019-2027 (2008)

Other Product Names

SH2 domain-containing protein 4A, Protein SH (2) A, Protein phosphatase 1 regulatory subunit 38, SH2D4A, PPP1R38, SH2A

Tested Applications

WB, IHC-P

Protein ID

74725117

Physical Properties

Liquid

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