SH2D4A Antibody
Product Specifications
Background
SH2D4A inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.
NCBI Gene ID
63898
Swiss Prot
Q9H788
Accession Number
Q9H788
Host
Rabbit
Reactivity
Human
Immunogen
This SH2D4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-67 amino acids from the N-terminal region of human SH2D4A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
53 kDa
Fragment
Rabbit Ig
Symbol
SH2D4A
NCBI Official Name
SH2 domain-containing protein 4A
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Li, T., et al. BMB Rep 42 (8) :516-522 (2009)
Background Reference 03
Venkatesan, K., et al. Nat. Methods 6 (1) :83-90 (2009)
Background Reference 04
Lapinski, P.E., et al. J. Immunol. 181 (3) :2019-2027 (2008)
Other Product Names
SH2 domain-containing protein 4A, Protein SH (2) A, Protein phosphatase 1 regulatory subunit 38, SH2D4A, PPP1R38, SH2A
Tested Applications
WB, IHC-P
Protein ID
74725117
Physical Properties
Liquid
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