CACNG6 Antibody

Product Specifications

Background

Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs) . Alternative splicing results in multiple transcript variants. Variants in this gene have been associated with aspirin-intolerant asthma.

NCBI Gene ID

59285

Swiss Prot

Q9BXT2

Accession Number

Q9BXT2

Host

Rabbit

Reactivity

Human

Immunogen

This CACNG6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-136 amino acids from the Central region of human CACNG6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

28 kDa

Fragment

Rabbit Ig

Symbol

CACNG6

NCBI Official Name

Voltage-dependent calcium channel gamma-6 subunit

NCBI Organism

Homo sapiens

Background Reference 01

Lee, J.S., et al. BMC Med. Genet. 11, 138 (2010) :

Background Reference 02

Chen, R.S., et al. Cell Biochem. Biophys. 47 (2) :178-186 (2007)

Background Reference 03

Chu, P.J., et al. Gene 280 (1-2), 37-48 (2001) :

Background Reference 04

Burgess, D.L., et al. Genomics 71 (3) :339-350 (2001)

Other Product Names

Voltage-dependent calcium channel gamma-6 subunit, Neuronal voltage-gated calcium channel gamma-6 subunit, CACNG6

Tested Applications

WB, IHC-P, IF

Protein ID

20532019

Physical Properties

Liquid

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