PDE3B Antibody

Product Specifications

Background

Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes; PDE3B may play a role in fat metabolism.

NCBI Gene ID

5140

Swiss Prot

Q13370

Accession Number

Q13370

Host

Rabbit

Reactivity

Human

Immunogen

This PDE3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-427 amino acids from the Central region of human PDE3B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

124 kDa

Fragment

Rabbit Ig

Symbol

PDE3B

NCBI Official Name

CGMP-inhibited 3',5'-cyclic phosphodiesterase B

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Yamano, Y., et al. Int. J. Cancer 126 (2) :437-449 (2010)

Background Reference 03

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Background Reference 04

Hanson, M.S., et al. Am. J. Physiol. Heart Circ. Physiol. 295 (2), H786-H793 (2008) :

Other Product Names

CGMP-inhibited 3',5'-cyclic phosphodiesterase B, CGIPDE1, CGIP1, Cyclic GMP-inhibited phosphodiesterase B, CGI-PDE B, PDE3B

Tested Applications

WB, IF, Flow

Protein ID

143811435

Physical Properties

Liquid

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