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RAD54 Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.

NCBI Gene ID

8438

Swiss Prot

Q92698

Accession Number

Q92698

Host

Rabbit

Reactivity

Human

Immunogen

This RAD54 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 634-663 amino acids from the C-terminal region of human RAD54.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Chicken, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=56-150

Calculated Molecular Weight

84 kDa

Fragment

Rabbit Ig

Symbol

RAD54L

NCBI Official Name

DNA repair and recombination protein RAD54-like

NCBI Organism

Homo sapiens

Background Reference 01

Liu, Y., et al. Carcinogenesis 31 (10) :1762-1769 (2010)

Background Reference 02

Briggs, F.B., et al. Am. J. Epidemiol. 172 (2) :217-224 (2010)

Background Reference 03

Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :

Background Reference 04

Guey, L.T., et al. Eur. Urol. 57 (2) :283-292 (2010)

Other Product Names

DNA repair and recombination protein RAD54-like, 364-, RAD54 homolog, hHR54, hRAD54, RAD54L, RAD54A

Tested Applications

WB, Flow

Protein ID

51316508

Physical Properties

Liquid

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