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TFAP4 Antibody

Product Specifications

Background

Transcription factors of the basic helix-loop-helix-zipper (bHLH-ZIP) family contain a basic domain, which is used for DNA binding, and HLH and ZIP domains, which are used for oligomerization. Transcription factor AP4 activates both viral and cellular genes by binding to the symmetrical DNA sequence CAGCTG (Mermod et al., 1988 [PubMed 2833704]; Hu et al., 1990 [PubMed 2123466]) .

NCBI Gene ID

7023

Swiss Prot

Q01664

Accession Number

Q01664

Host

Rabbit

Reactivity

Human

Immunogen

This TFAP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-154 amino acids from the Central region of human TFAP4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

39 kDa

Fragment

Rabbit Ig

Symbol

TFAP4

NCBI Official Name

Transcription factor AP-4

NCBI Organism

Homo sapiens

Background Reference 01

Ku, W.C., et al. Mol. Cell Proteomics 8 (9) :2034-2050 (2009)

Background Reference 02

Cao, J., et al. Int. J. Surg. Pathol. 17 (1) :16-21 (2009)

Background Reference 03

Jung, P., et al. Proc. Natl. Acad. Sci. U.S.A. 105 (39) :15046-15051 (2008)

Background Reference 04

Pons, J., et al. Biochemistry 47 (1) :14-29 (2008)

Other Product Names

Transcription factor AP-4, Activating enhancer-binding protein 4, Class C basic helix-loop-helix protein 41, bHLHc41, TFAP4, BHLHC41

Tested Applications

WB, Flow

Protein ID

1729833

Physical Properties

Liquid

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