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TFIIIC90 Antibody

Product Specifications

Background

Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box.

NCBI Gene ID

9329

Swiss Prot

Q9UKN8

Accession Number

Q9UKN8

Host

Rabbit

Reactivity

Mouse

Immunogen

This TFIIIC90 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-244 amino acids from the N-terminal region of human TFIIIC90.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

92 kDa

Fragment

Rabbit Ig

Symbol

GTF3C4

NCBI Official Name

General transcription factor 3C polypeptide 4

NCBI Organism

Homo sapiens

Background Reference 01

Joubert, B.R., et al. Genome Med (3), 17 (2010) :

Background Reference 02

Dumay-Odelot, H., et al. J. Biol. Chem. 282 (23) :17179-17189 (2007)

Background Reference 03

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Background Reference 04

Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (33) :12130-12135 (2004)

Other Product Names

General transcription factor 3C polypeptide 4, TF3C-delta, Transcription factor IIIC 90 kDa subunit, TFIIIC 90 kDa subunit, TFIIIC90, Transcription factor IIIC subunit delta, GTF3C4

Tested Applications

WB, Flow

Protein ID

212276467

Physical Properties

Liquid

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