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MGP Antibody

Product Specifications

Background

The protein encoded by this gene is secreted and likely acts as an inhibitor of bone formation. The encoded protein is found in the organic matrix of bone and cartilage. Defects in this gene are a cause of Keutel syndrome (KS) . Two transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

4256

Swiss Prot

P08493

Accession Number

P08493

Host

Rabbit

Reactivity

Human

Immunogen

This MGP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the Central region of human MGP.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

12 kDa

Fragment

Rabbit Ig

Symbol

MGP

NCBI Official Name

Matrix Gla protein

NCBI Organism

Homo sapiens

Background Reference 01

Romero, R., et al. Am. J. Obstet. Gynecol. (2010) In press :

Background Reference 02

Bailey, S.D., et al. Diabetes Care (2010) In press :

Background Reference 03

Parker, B.D., et al. Ann. Intern. Med. 152 (10) :640-648 (2010)

Background Reference 04

Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :

Other Product Names

Matrix Gla protein, MGP, Cell growth-inhibiting gene 36 protein, MGP, MGLAP

Tested Applications

WB, IHC-P, Flow

Protein ID

118572668

Physical Properties

Liquid

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