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ZNF384 Antibody

Product Specifications

Background

This gene contains long CAG trinucleotide repeats coding consecutive glutamine residues. The gene product may functions as a transcription factor, with a potential role in the regulation of neurodevelopment or neuroplasticity. The protein appears to bind and regulate the promoters of MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Multiple transcript variants encoding several isoforms have been found for this gene.

NCBI Gene ID

171017

Swiss Prot

Q8TF68

Accession Number

Q8TF68

Host

Rabbit

Reactivity

Human

Immunogen

This ZNF384 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-559 amino acids from the C-terminal region of human ZNF384.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

63 kDa

Fragment

Rabbit Ig

Symbol

ZNF384

NCBI Official Name

Zinc finger protein 384

NCBI Organism

Homo sapiens

Background Reference 01

Alves, J., et al. Biochem. Biophys. Res. Commun. 384 (4) :495-500 (2009)

Background Reference 02

Zhong, C.H., et al. Leukemia 22 (4) :723-729 (2008)

Background Reference 03

Janssen, H., et al. Exp. Cell Res. 312 (7) :1194-1204 (2006)

Background Reference 04

La Starza, R., et al. Leukemia 19 (9) :1696-1699 (2005)

Other Product Names

Zinc finger protein 384, CAG repeat protein 1, CAS-interacting zinc finger protein, Nuclear matrix transcription factor 4, Nuclear matrix protein 4, Trinucleotide repeat-containing gene 1 protein, ZNF384, CAGH1, CIZ, NMP4, TNRC1

Tested Applications

WB, Flow

Protein ID

296453052

Physical Properties

Liquid

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