ZNF384 Antibody
Product Specifications
Background
This gene contains long CAG trinucleotide repeats coding consecutive glutamine residues. The gene product may functions as a transcription factor, with a potential role in the regulation of neurodevelopment or neuroplasticity. The protein appears to bind and regulate the promoters of MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Multiple transcript variants encoding several isoforms have been found for this gene.
NCBI Gene ID
171017
Swiss Prot
Q8TF68
Accession Number
Q8TF68
Host
Rabbit
Reactivity
Human
Immunogen
This ZNF384 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-559 amino acids from the C-terminal region of human ZNF384.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
63 kDa
Fragment
Rabbit Ig
Symbol
ZNF384
NCBI Official Name
Zinc finger protein 384
NCBI Organism
Homo sapiens
Background Reference 01
Alves, J., et al. Biochem. Biophys. Res. Commun. 384 (4) :495-500 (2009)
Background Reference 02
Zhong, C.H., et al. Leukemia 22 (4) :723-729 (2008)
Background Reference 03
Janssen, H., et al. Exp. Cell Res. 312 (7) :1194-1204 (2006)
Background Reference 04
La Starza, R., et al. Leukemia 19 (9) :1696-1699 (2005)
Other Product Names
Zinc finger protein 384, CAG repeat protein 1, CAS-interacting zinc finger protein, Nuclear matrix transcription factor 4, Nuclear matrix protein 4, Trinucleotide repeat-containing gene 1 protein, ZNF384, CAGH1, CIZ, NMP4, TNRC1
Tested Applications
WB, Flow
Protein ID
296453052
Physical Properties
Liquid
Curated Selection
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