PELP1 Antibody

Product Specifications

Background

PELP1 is a coactivator of estrogen receptor (see ESR1; MIM 133430) -mediated transcription and a corepressor of other nuclear hormone receptors and sequence-specific transcription factors (Choi et al., 2004 [PubMed 15456770]) .

NCBI Gene ID

27043

Swiss Prot

Q8IZL8

Accession Number

Q8IZL8

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This PELP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 744-771 amino acids from the Central region of human PELP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

120 kDa

Fragment

Rabbit Ig

Symbol

PELP1

NCBI Official Name

Proline-, glutamic acid- and leucine-rich protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Nair, S.S., et al. EMBO Rep. 11 (6) :438-444 (2010)

Background Reference 02

Habashy, H.O., et al. Breast Cancer Res. Treat. 120 (3) :603-612 (2010)

Background Reference 03

Vadlamudi, R.K., et al. J. Steroid Biochem. Mol. Biol. 118 (4-5), 211-218 (2010) :

Background Reference 04

Tzelepi, V., et al. Virchows Arch. 454 (1) :41-53 (2009)

Other Product Names

Proline-, glutamic acid- and leucine-rich protein 1, Modulator of non-genomic activity of estrogen receptor, Transcription factor HMX3, PELP1, HMX3, MNAR