MYLK3 Antibody
Product Specifications
Background
Phosphorylation of cardiac myosin heavy chains (see MYH7B, MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocytes (Chan et al., 2008 [PubMed 18202317]) .
NCBI Gene ID
91807
Swiss Prot
Q32MK0
Accession Number
Q32MK0
Host
Rabbit
Reactivity
Human
Immunogen
This MYLK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 535-562 amino acids from the Central region of human MYLK3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
88 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MYLK3
NCBI Official Name
Myosin light chain kinase 3
NCBI Organism
Homo sapiens
Background Reference 01
Al-Sadi, R., et al. J. Immunol. 180 (8) :5653-5661 (2008)
Background Reference 02
Chan, J.Y., et al. Circ. Res. 102 (5) :571-580 (2008)
Background Reference 03
Seguchi, O., et al. J. Clin. Invest. 117 (10) :2812-2824 (2007)
Other Product Names
Myosin light chain kinase 3, Cardiac-MyBP-C-associated Ca/CaM kinase, Cardiac-MLCK, MYLK3, MLCK
Tested Applications
WB
Protein ID
254763411
Physical Properties
Liquid
Curated Selection
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