FRAT2 Antibody
Product Specifications
Background
The protein encoded by this intronless gene belongs to the GSK-3-binding protein family. Studies show that this protein plays a role as a positive regulator of the WNT signaling pathway. It may be upregulated in tumor progression.
NCBI Gene ID
23401
Swiss Prot
O75474
Accession Number
O75474
Host
Rabbit
Reactivity
Human
Immunogen
This FRAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-230 amino acids from the C-terminal region of human FRAT2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
24 kDa
Fragment
Rabbit Ig
Symbol
FRAT2
NCBI Official Name
GSK-3-binding protein FRAT2
NCBI Organism
Homo sapiens
Background Reference 01
Lee, D.Y., et al. Menopause 17 (5) :1064-1070 (2010)
Background Reference 02
Liu, G.P., et al. Neurobiol. Aging 29 (9) :1348-1358 (2008)
Background Reference 03
Stoothoff, W.H., et al. J. Biol. Chem. 280 (1) :270-276 (2005)
Background Reference 04
Deloukas, P., et al. Nature 429 (6990) :375-381 (2004)
Other Product Names
GSK-3-binding protein FRAT2, Frequently rearranged in advanced T-cell lymphomas 2, FRAT-2, FRAT2
Tested Applications
WB, IHC-P, IF
Physical Properties
Liquid
Curated Selection
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