PTPN20A Antibody
Product Specifications
Background
The product of this gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes and several are mutated in human diseases. Chromosome 10q contains a segmental duplication resulting in multiple copies of the protein tyrosine phosphatase, non-receptor type 20 gene. The two nearly identical copies are designated as PTPN20A and PTPN20B. A third copy is only partially duplicated and contains a pseudogene, designated as PTPN20C. This gene encodes the more telomeric copy, PTPN20B. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
NCBI Gene ID
26095
Swiss Prot
Q4JDL3
Accession Number
Q4JDL3
Host
Rabbit
Reactivity
Human
Immunogen
This PTPN20A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-207 amino acids from the Central region of human PTPN20A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
48 kDa
Fragment
Rabbit Ig
Symbol
PTPN20A
NCBI Official Name
Tyrosine-protein phosphatase non-receptor type 20
NCBI Organism
Homo sapiens
Background Reference 01
Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)
Background Reference 02
Fodero-Tavoletti, M.T., et al. Biochem. J. 389 (PT 2), 343-354 (2005) :
Other Product Names
Tyrosine-protein phosphatase non-receptor type 20, hPTPN20, PTPN20A
Tested Applications
WB, IHC-P, Flow
Protein ID
121944218
Physical Properties
Liquid
Curated Selection
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