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RB1CC1 Antibody

Product Specifications

Background

The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

NCBI Gene ID

9821

Swiss Prot

Q8TDY2

Accession Number

Q8TDY2

Host

Rabbit

Reactivity

Mouse

Immunogen

This RB1CC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 489-515 amino acids from the Central region of human RB1CC1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=56-041

Calculated Molecular Weight

183 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RB1CC1

NCBI Official Name

RB1-inducible coiled-coil protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Liu, C.Y., et al. Carcinogenesis 31 (7) :1259-1263 (2010)

Background Reference 02

Guey, L.T., et al. Eur. Urol. 57 (2) :283-292 (2010)

Background Reference 03

Chano, T., et al. PLoS ONE (6), E11404 (2010) :

Background Reference 04

Paun, B.C., et al. PLoS ONE (11), E7715 (2009) :

Other Product Names

RB1-inducible coiled-coil protein 1, FAK family kinase-interacting protein of 200 kDa, FIP200, RB1CC1, KIAA0203, RBICC

Tested Applications

WB

Protein ID

160359050

Physical Properties

Liquid

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