CMGA Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.
NCBI Gene ID
1113
Swiss Prot
P10645
Accession Number
P10645
Host
Rabbit
Reactivity
Human
Immunogen
This CMGA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 376-404 amino acids from the C-terminal region of human CMGA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=56-038
Calculated Molecular Weight
51 kDa
Fragment
Rabbit Ig
Symbol
CHGA
NCBI Official Name
Chromogranin-A
NCBI Organism
Homo sapiens
Background Reference 01
Ezzi, S.A., et al. J. Neurochem. 115 (5) :1102-1111 (2010)
Background Reference 02
Ma, Z., et al. J. Urol. 184 (3) :1182-1188 (2010)
Background Reference 03
Ramella, R., et al. J. Cell. Biochem. 110 (1) :70-79 (2010)
Background Reference 04
Dag, E., et al. Peptides 31 (5) :932-937 (2010)
Other Product Names
Chromogranin-A, CgA, Pituitary secretory protein I, SP-I, Vasostatin-1, Vasostatin I, Vasostatin-2, Vasostatin II, EA-92, ES-43, Pancreastatin, SS-18, WA-8, WE-14, LF-19, AL-11, GV-19, GR-44, ER-37, CHGA
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
215274270
Physical Properties
Liquid
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