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CMGA Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.

NCBI Gene ID

1113

Swiss Prot

P10645

Accession Number

P10645

Host

Rabbit

Reactivity

Human

Immunogen

This CMGA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 376-404 amino acids from the C-terminal region of human CMGA.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Symbol

CHGA

NCBI Official Name

Chromogranin-A

NCBI Organism

Homo sapiens

Background Reference 01

Ezzi, S.A., et al. J. Neurochem. 115 (5) :1102-1111 (2010)

Background Reference 02

Ma, Z., et al. J. Urol. 184 (3) :1182-1188 (2010)

Background Reference 03

Ramella, R., et al. J. Cell. Biochem. 110 (1) :70-79 (2010)

Background Reference 04

Dag, E., et al. Peptides 31 (5) :932-937 (2010)

Other Product Names

Chromogranin-A, CgA, Pituitary secretory protein I, SP-I, Vasostatin-1, Vasostatin I, Vasostatin-2, Vasostatin II, EA-92, ES-43, Pancreastatin, SS-18, WA-8, WE-14, LF-19, AL-11, GV-19, GR-44, ER-37, CHGA

Tested Applications

WB, IHC-P, IF, Flow

Protein ID

215274270

Physical Properties

Liquid

Frequently Asked Questions

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