SOX1 Antibody

Product Specifications

Background

This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development.

NCBI Gene ID

6656

Swiss Prot

O00570

Accession Number

O00570

Host

Rabbit

Reactivity

Human

Immunogen

This SOX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47-76 amino acids from the N-terminal region of human SOX1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Chicken, Zebrafish, Monkey, Mouse, Xenopus

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

39 kDa

Fragment

Rabbit Ig

Symbol

SOX1

NCBI Official Name

Transcription factor SOX-1

NCBI Organism

Homo sapiens

Background Reference 01

Panayi, H., et al. J. Neurosci. 30 (37) :12274-12280 (2010)

Background Reference 02

Phi, J.H., et al.Neurosurg Pediatr 5 (6) :608-614 (2010)

Background Reference 03

Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :

Background Reference 04

Titulaer, M.J., et al. J. Clin. Oncol. 27 (26) :4260-4267 (2009)

Other Product Names

Transcription factor SOX-1, SOX1

Tested Applications

WB, Flow

Physical Properties

Liquid

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