ID1 Antibody

Product Specifications

Background

The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

NCBI Gene ID

3397

Swiss Prot

P41134

Accession Number

P41134

Host

Rabbit

Reactivity

Human, Rat

Immunogen

This ID1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-93 amino acids from the Central region of human ID1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

16 kDa

Fragment

Rabbit Ig

Symbol

ID1

NCBI Official Name

DNA-binding protein inhibitor ID-1

NCBI Organism

Homo sapiens

Background Reference 01

Qian, T., et al. Oncogene 29 (43) :5818-5827 (2010)

Background Reference 02

Hamajima, Y., et al. Cell Prolif. 43 (5) :457-463 (2010)

Background Reference 03

Yang, J., et al. Circ. Res. 107 (2) :252-262 (2010)

Background Reference 04

Phi, J.H., et al.Neurosurg Pediatr 5 (6) :608-614 (2010)

Other Product Names

DNA-binding protein inhibitor ID-1, Class B basic helix-loop-helix protein 24, bHLHb24, Inhibitor of DNA binding 1, Inhibitor of differentiation 1, ID1, BHLHB24, ID