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HOXB6 Antibody

Product Specifications

Background

This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer.

NCBI Gene ID

3216

Swiss Prot

P17509

Accession Number

P17509

Host

Rabbit

Reactivity

Mouse

Immunogen

This HOXB6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-155 amino acids from the Central region of human HOXB6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

25 kDa

Fragment

Rabbit Ig

Symbol

HOXB6

NCBI Official Name

Homeobox protein Hox-B6

NCBI Organism

Homo sapiens

Background Reference 01

Ferrai, C., et al. Mol. Biol. Cell 20 (15) :3543-3551 (2009)

Background Reference 02

Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)

Background Reference 03

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Background Reference 04

Chen, T., et al. Eur. J. Hum. Genet. 15 (1) :23-28 (2007)

Other Product Names

Homeobox protein Hox-B6, Homeobox protein Hox-22, Homeobox protein Hox-2B, Homeobox protein Hu-2, HOXB6, HOX2B

Tested Applications

WB, IHC-P

Protein ID

116242515

Physical Properties

Liquid

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