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MEF2D Antibody

Product Specifications

Background

Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT] (4) TAR-3', found in numerous muscle-specific, growth factor-and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis (By similarity) .

NCBI Gene ID

4209

Swiss Prot

Q14814

Accession Number

Q14814

Host

Rabbit

Reactivity

Human

Immunogen

This MEF2D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-136 amino acids from the N-terminal region of human MEF2D.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

56 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MEF2D

NCBI Official Name

Myocyte-specific enhancer factor 2D

NCBI Organism

Homo sapiens

Background Reference 01

Jablonski, K.A., et al. Diabetes 59 (10) :2672-2681 (2010)

Background Reference 02

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 03

Aude-Garcia, C., et al. Biochem. J. 430 (2) :237-244 (2010)

Background Reference 04

Czubryt, M.P., et al. J. Biol. Chem. 285 (22) :16942-16950 (2010)

Other Product Names

Myocyte-specific enhancer factor 2D, MEF2D

Tested Applications

WB

Protein ID

2500876

Physical Properties

Liquid

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