CREB1 Antibody

Product Specifications

Background

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.

NCBI Gene ID

1385

Swiss Prot

P16220

Accession Number

P16220

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This CREB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 105-132 amino acids from the Central region of human CREB1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

37 kDa

Fragment

Rabbit Ig

Symbol

CREB1

NCBI Official Name

Cyclic AMP-responsive element-binding protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Jablonski, K.A., et al. Diabetes 59 (10) :2672-2681 (2010) Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010) Chen, G., et al. J. Neurosci. 30 (39) :13066-13077 (2010) Serretti, A., et al.Affect Disord (2010) In pressMelnikova, V.O., et al. PLoS ONE (8), E12452 (2010) :