SSH3 Antibody

Product Specifications

Background

The ADF (actin-depolymerizing factor) /cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329) . The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]) .

NCBI Gene ID

54961

Swiss Prot

Q8TE77

Accession Number

Q8TE77

Host

Rabbit

Reactivity

Human

Immunogen

This SSH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 575-602 amino acids from the C-terminal region of human SSH3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

73 kDa

Fragment

Rabbit Ig

Symbol

SSH3

NCBI Official Name

Protein phosphatase Slingshot homolog 3

NCBI Organism

Homo sapiens

Background Reference 01

Kousaka, K., et al. Genesis 46 (5) :246-255 (2008)

Background Reference 02

Kligys, K., et al. J. Biol. Chem. 282 (44) :32520-32528 (2007)

Background Reference 03

Beausoleil, S.A., et al. Nat. Biotechnol. 24 (10) :1285-1292 (2006)

Background Reference 04

Soosairajah, J., et al. EMBO J. 24 (3) :473-486 (2005)

Other Product Names

Protein phosphatase Slingshot homolog 3, SSH-like protein 3, SSH-3L, hSSH-3L, SSH3, SSH3L

Tested Applications

WB, IHC-P, IF, Flow

Protein ID

82582268

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

JH916006 1 Each

6,7-dihydro-5H-cyclopenta[b]pyridine-3-carboxylic acid

Ask

View Details

RDC0151 10 µg

Human Neuromedin B R/NMBR VersaClone cDNA

Ask

View Details

CS532499 5x 5 µm

Frozen Tissue Sections, Kidney

Ask

View Details

NBP2-70909APC 0.1 mL

Mouse Monoclonal HOXC10 Antibody (OTI5C10) [Allophycocyanin]

Ask

View Details