SSH3 Antibody
Product Specifications
Background
The ADF (actin-depolymerizing factor) /cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329) . The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]) .
NCBI Gene ID
54961
Swiss Prot
Q8TE77
Accession Number
Q8TE77
Host
Rabbit
Reactivity
Human
Immunogen
This SSH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 575-602 amino acids from the C-terminal region of human SSH3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
73 kDa
Fragment
Rabbit Ig
Symbol
SSH3
NCBI Official Name
Protein phosphatase Slingshot homolog 3
NCBI Organism
Homo sapiens
Background Reference 01
Kousaka, K., et al. Genesis 46 (5) :246-255 (2008)
Background Reference 02
Kligys, K., et al. J. Biol. Chem. 282 (44) :32520-32528 (2007)
Background Reference 03
Beausoleil, S.A., et al. Nat. Biotechnol. 24 (10) :1285-1292 (2006)
Background Reference 04
Soosairajah, J., et al. EMBO J. 24 (3) :473-486 (2005)
Other Product Names
Protein phosphatase Slingshot homolog 3, SSH-like protein 3, SSH-3L, hSSH-3L, SSH3, SSH3L
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
82582268
Physical Properties
Liquid
Frequently Asked Questions
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