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PAP Antibody

Product Specifications

Background

Polymerase that creates the 3'-poly (A) tail of mRNA's. Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites. May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus.

NCBI Gene ID

10914

Swiss Prot

P51003

Accession Number

P51003

Host

Rabbit

Reactivity

Human

Immunogen

This PAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 407-435 amino acids from the Central region of human PAP.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

83 kDa

Fragment

Rabbit Ig

Symbol

PAPOLA

NCBI Official Name

Poly (A) polymerase alpha

NCBI Organism

Homo sapiens

Background Reference 01

Rapti, A., et al. Mol. Cell. Biochem. 340 (1-2), 91-96 (2010) :

Background Reference 02

Nan, H., et al. J. Invest. Dermatol. 129 (9) :2250-2257 (2009)

Background Reference 03

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Background Reference 04

Dettwiler, S., et al. J. Biol. Chem. 279 (34) :35788-35797 (2004)

Other Product Names

Poly (A) polymerase alpha, PAP-alpha, Polynucleotide adenylyltransferase alpha, PAPOLA, PAP

Tested Applications

WB, IHC-P

Protein ID

59803092

Physical Properties

Liquid

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