OTX2 Antibody

Product Specifications

Background

This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants may exist, but their full length sequences have not been determined.

NCBI Gene ID

5015

Swiss Prot

P32243

Accession Number

P32243

Host

Rabbit

Reactivity

Human

Immunogen

This OTX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-289 amino acids from the C-terminal region of human OTX2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Zebrafish, Xenopus

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

32 kDa

Fragment

Rabbit Ig

Symbol

OTX2

NCBI Official Name

Homeobox protein OTX2

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Masuda, T., et al. J. Biol. Chem. 285 (35) :26933-26944 (2010)

Background Reference 03

Gonzalez-Rodriguez, J., et al. BrOphthalmol 94 (8) :1100-1104 (2010)

Background Reference 04

Chung, C.Y., et al. Brain 133 (PT 7), 2022-2031 (2010) :

Other Product Names

Homeobox protein OTX2, Orthodenticle homolog 2, OTX2

Tested Applications

Physical Properties

Liquid

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