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NCL Antibody

Product Specifications

Background

Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.

NCBI Gene ID

4691

Swiss Prot

P19338

Accession Number

P19338

Host

Rabbit

Reactivity

Human

Immunogen

This NCL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-455 amino acids from the Central region of human NCL.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

77 kDa

Fragment

Rabbit Ig

Symbol

NCL

NCBI Official Name

Nucleolin

NCBI Organism

Homo sapiens

Background Reference 01

Ishimaru, D., et al. J. Biol. Chem. 285 (35) :27182-27191 (2010)

Background Reference 02

Tulchin, N., et al. Am. J. Pathol. 176 (3) :1203-1214 (2010)

Background Reference 03

Strang, B.L., et al. J. Virol. 84 (4) :1771-1784 (2010)

Background Reference 04

Bertrand, L., et al. J. Virol. 84 (1) :109-118 (2010)

Other Product Names

Nucleolin, Protein C23, NCL

Tested Applications

WB, IHC-P, IF

Protein ID

90110781

Physical Properties

Liquid

Frequently Asked Questions

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