GFER Antibody

Product Specifications

Background

The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS) . The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1) . The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene.

NCBI Gene ID

2671

Swiss Prot

P55789

Accession Number

P55789

Host

Rabbit

Reactivity

Mouse

Immunogen

This GFER antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 173-202 amino acids from the C-terminal region of human GFER.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

23 kDa

Fragment

Rabbit Ig

Symbol

GFER

NCBI Official Name

FAD-linked sulfhydryl oxidase ALR

NCBI Organism

Homo sapiens

Background Reference 01

Dong, L.Y., et al. Biochem. J. 431 (2) :277-287 (2010)

Background Reference 02

Li, W., et al. FEBS Lett. 584 (18) :3929-3935 (2010)

Background Reference 03

Daithankar, V.N., et al. Biochemistry 49 (31) :6737-6745 (2010)

Background Reference 04

Dayoub, R., et al. Biochem. Biophys. Res. Commun. 395 (4) :465-470 (2010)

Other Product Names

FAD-linked sulfhydryl oxidase ALR, Augmenter of liver regeneration, hERV1, Hepatopoietin, GFER, ALR, HERV1, HPO

Tested Applications

WB, Flow

Protein ID

218511915

Physical Properties

Liquid

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