CHRND Antibody

Product Specifications

Background

The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

NCBI Gene ID

1144

Swiss Prot

Q07001

Accession Number

Q07001

Host

Rabbit

Reactivity

Human

Immunogen

This CHRND antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-196 amino acids from the Central region of human CHRND.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

59 kDa

Fragment

Rabbit Ig

Symbol

CHRND

NCBI Official Name

Acetylcholine receptor subunit delta

NCBI Organism

Homo sapiens

Background Reference 01

Saccone, N.L., et al. Genes Brain Behav. 9 (7) :741-750 (2010)

Background Reference 02

Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34 (5) :800-812 (2010)

Background Reference 03

Gratacos, M., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :

Background Reference 04

Saccone, N.L., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 150B (4), 453-466 (2009) :

Other Product Names

Acetylcholine receptor subunit delta, CHRND, ACHRD

Tested Applications

WB, Flow

Protein ID

543759

Physical Properties

Liquid

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