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DKK4 Antibody

Product Specifications

Background

This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. Activity of this protein is modulated by binding to the Wnt co-receptor and the co-factor kremen 2.

NCBI Gene ID

27121

Swiss Prot

Q9UBT3

Accession Number

Q9UBT3

Host

Rabbit

Reactivity

Human

Immunogen

This DKK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-189 amino acids from the C-terminal region of human DKK4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

25 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

DKK4

NCBI Official Name

Dickkopf-related protein 4

NCBI Organism

Homo sapiens

Background Reference 01

Hosgood, H.D. III, et al. Occup Environ Med 66 (12) :848-853 (2009)

Background Reference 02

Yerges, L.M., et al. J. Bone Miner. Res. 24 (12) :2039-2049 (2009)

Background Reference 03

Hirata, H., et al. Cancer 115 (19) :4488-4503 (2009)

Background Reference 04

Matsui, A., et al. Cancer Sci. 100 (10) :1923-1930 (2009)

Other Product Names

Dickkopf-related protein 4, Dickkopf-4, Dkk-4, hDkk-4, Dickkopf-related protein 4 short form, DKK4

Tested Applications

WB

Protein ID

13124092

Physical Properties

Liquid

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