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GALNS Antibody

Product Specifications

Background

This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder. [provided by RefSeq].

NCBI Gene ID

2588

Swiss Prot

P34059

Accession Number

P34059

Host

Rabbit

Reactivity

Human

Immunogen

This GALNS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-263 amino acids from the Central region of human GALNS.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Pig, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=55-960

Calculated Molecular Weight

58 kDa

Fragment

Rabbit Ig

Symbol

GALNS

NCBI Official Name

N-acetylgalactosamine-6-sulfatase

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Bank, R.A., et al. Mol. Genet. Metab. 97 (3) :196-201 (2009)

Background Reference 03

Yan, S., et al. Biopolymers 92 (5) :399-404 (2009)

Background Reference 04

Carraresi, L., et al. Clin. Chim. Acta 397 (1-2), 72-76 (2008) :

Other Product Names

N-acetylgalactosamine-6-sulfatase, Chondroitinsulfatase, Chondroitinase, Galactose-6-sulfate sulfatase, GalN6S, N-acetylgalactosamine-6-sulfate sulfatase, GalNAc6S sulfatase, GALNS

Tested Applications

WB, IHC-P, IF, Flow

Protein ID

462148

Physical Properties

Liquid

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