LILRA5 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].

NCBI Gene ID

353514

Swiss Prot

A6NI73

Accession Number

A6NI73

Host

Rabbit

Reactivity

Human

Immunogen

This LILRA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-85 amino acids from the N-terminal region of human LILRA5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

33 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

LILRA5

NCBI Official Name

Leukocyte immunoglobulin-like receptor subfamily A member 5

NCBI Organism

Homo sapiens

Background Reference 01

Mosbruger, T.L., et al. J. Infect. Dis. 201 (9) :1371-1380 (2010)

Background Reference 02

Jones, D.C., et al. Eur. J. Immunol. 39 (11) :3195-3206 (2009)

Background Reference 03

Shiroishi, M., et al. J. Biol. Chem. 281 (28) :19536-19544 (2006)

Background Reference 04

Borges, L., et al. Blood 101 (4) :1484-1486 (2003)

Other Product Names

Leukocyte immunoglobulin-like receptor subfamily A member 5, CD85 antigen-like family member F, Immunoglobulin-like transcript 11, ILT-11, Leukocyte immunoglobulin-like receptor 9, LIR-9, CD85f, LILRA5, ILT11, LILRB7, LIR9