CACNG8 Antibody

Product Specifications

Background

The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP) . TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type II TARP and a calcium channel gamma subunit. The mRNA for this gene is believed to initiate translation from a non-AUG (CUG) start codon.

NCBI Gene ID

59283

Swiss Prot

Q8WXS5

Accession Number

Q8WXS5

Host

Rabbit

Reactivity

Mouse

Immunogen

This CACNG8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the N-terminal region of human CACNG8.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

43 kDa

Fragment

Rabbit Ig

Symbol

CACNG8

NCBI Official Name

Voltage-dependent calcium channel gamma-8 subunit

NCBI Organism

Homo sapiens

Background Reference 01

Sager, C., et al. Neurobiology 158 (1) :45-54 (2009)

Background Reference 02

Correia, S.S., et al. Nat. Neurosci. 11 (4) :457-466 (2008)

Background Reference 03

Chen, R.S., et al. Cell Biochem. Biophys. 47 (2) :178-186 (2007)

Background Reference 04

Chu, P.J., et al. Gene 280 (1-2), 37-48 (2001) :

Other Product Names

Voltage-dependent calcium channel gamma-8 subunit, Neuronal voltage-gated calcium channel gamma-8 subunit, Transmembrane AMPAR regulatory protein gamma-8, TARP gamma-8, CACNG8, CACNG6