ISWI Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein.
NCBI Gene ID
8467
Swiss Prot
O60264
Accession Number
O60264
Host
Rabbit
Reactivity
Human
Immunogen
This ISWI antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 946-975 amino acids from the C-terminal region of human ISWI.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
122 kDa
Fragment
Rabbit Ig
Symbol
SMARCA5
NCBI Official Name
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5
NCBI Organism
Homo sapiens
Background Reference 01
Goldman, J.A., et al. J. Biol. Chem. 285 (7) :4645-4651 (2010)
Background Reference 02
He, X., et al. Biochemistry 47 (27) :7025-7033 (2008)
Background Reference 03
Sheu, J.J., et al. Cancer Res. 68 (11) :4050-4057 (2008)
Background Reference 04
Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)
Other Product Names
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5, 364-, Sucrose nonfermenting protein 2 homolog, hSNF2H, SMARCA5, SNF2H, WCRF135
Tested Applications
WB, Flow
Physical Properties
Liquid
Frequently Asked Questions
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