Neuropilin-2 Antibody
Product Specifications
Background
This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF) . This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
NCBI Gene ID
8828
Swiss Prot
O60462
Accession Number
O60462
Host
Rabbit
Reactivity
Human
Immunogen
This Neuropilin-2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 798-827 amino acids from the C-terminal region of human Neuropilin-2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
105 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NRP2
NCBI Official Name
Neuropilin-2
NCBI Organism
Homo sapiens
Background Reference 01
Rey-Gallardo, A., et al. Glycobiology 20 (9) :1139-1146 (2010)
Background Reference 02
Geretti, E., et al. Mol. Cancer Res. 8 (8) :1063-1073 (2010)
Background Reference 03
Guo-ping, W., et al. Ann Plast Surg 65 (1) :80-84 (2010)
Background Reference 04
Nasarre, C., et al. Cell Adh Migr 3 (4) :383-389 (2009)
Other Product Names
Neuropilin-2, Vascular endothelial cell growth factor 165 receptor 2, NRP2, VEGF165R2
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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