Myeloperoxidase Antibody

Product Specifications

Background

Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. [provided by RefSeq].

NCBI Gene ID

4353

Swiss Prot

P05164

Accession Number

P05164

Host

Rabbit

Reactivity

Human

Immunogen

This Myeloperoxidase antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-89 amino acids from the N-terminal region of human Myeloperoxidase.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology, Obesity

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

84 kDa

Fragment

Rabbit Ig

Symbol

MPO

NCBI Official Name

Myeloperoxidase

NCBI Organism

Homo sapiens

Background Reference 01

Banerjee, M., et al. Toxicol. Appl. Pharmacol. 249 (1) :47-54 (2010)

Background Reference 02

Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)

Background Reference 03

Nahon, P., et al. Antioxid. Redox Signal. (2010) In press :

Background Reference 04

Wang, Y., et al. J. Huazhong Univ. Sci. Technol. Med. Sci. 30 (4) :437-442 (2010)

Other Product Names

Myeloperoxidase, MPO, Myeloperoxidase, 89 kDa myeloperoxidase, 84 kDa myeloperoxidase, Myeloperoxidase light chain, Myeloperoxidase heavy chain, MPO

Tested Applications

WB, Flow

Protein ID

129825

Physical Properties

Liquid

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