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MAML1 Antibody

Product Specifications

Background

This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.

NCBI Gene ID

9794

Swiss Prot

Q92585

Accession Number

Q92585

Host

Rabbit

Reactivity

Human

Immunogen

This MAML1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-225 amino acids from the Central region of human MAML1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

108 kDa

Fragment

Rabbit Ig

Symbol

MAML1

NCBI Official Name

Mastermind-like protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Lindberg, M.J., et al. FASEB J. 24 (7) :2396-2404 (2010)

Background Reference 03

Hao, L., et al. Oncogene 29 (2) :201-213 (2010)

Background Reference 04

Saint Just Ribeiro, M., et al. Curr. Protein Pept. Sci. 10 (6) :570-576 (2009)

Other Product Names

HGNC:13632

Tested Applications

WB, Flow

Protein ID

68565602

Physical Properties

Liquid

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