NTHL1 Antibody

Product Specifications

Background

The protein encoded by this gene is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity.

NCBI Gene ID

4913

Swiss Prot

P78549

Accession Number

P78549

Host

Rabbit

Reactivity

Human

Immunogen

This NTHL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-117 amino acids from the Central region of human NTHL1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

34 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NTHL1

NCBI Official Name

Endonuclease III-like protein 1 {ECO:0000255|HAMAP-Rule:MF_03183}

NCBI Organism

Homo sapiens

Background Reference 01

Wang, W., et al. Nucleic Acids Res. (2010) In press :

Background Reference 02

Arora, M., et al. Leukemia 24 (8) :1470-1475 (2010)

Background Reference 03

Thyagarajan, B., et al. Biol. Blood Marrow Transplant. 16 (8) :1084-1089 (2010)

Background Reference 04

Briggs, F.B., et al. Am. J. Epidemiol. 172 (2) :217-224 (2010)

Other Product Names

Endonuclease III-like protein 1 {ECO:0000255|HAMAP-Rule:MF_03183}, hNTH1, 322- {ECO:0000255|HAMAP-Rule:MF_03183}, 429918 {ECO:0000255|HAMAP-Rule:MF_03183}, Bifunctional DNA N-glycoslyase/DNA- (apurinic or apyrimidinic site) lyase {ECO:0000255|HAMAP-Rule:MF_03183}, DNA glycoslyase/AP lyase {ECO:0000255|HAMAP-Rule:MF_03183}, NTHL1 {ECO:0000255|HAMAP-Rule:MF_03183}, NTH1, OCTS3