ZC3H8 Antibody
Product Specifications
Background
Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity) . Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
NCBI Gene ID
84524
Swiss Prot
Q8N5P1
Accession Number
Q8N5P1
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This ZC3H8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-81 amino acids from the N-terminal region of human ZC3H8.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=55-863
Calculated Molecular Weight
34 kDa
Fragment
Rabbit Ig
Symbol
ZC3H8
NCBI Official Name
Zinc finger CCCH domain-containing protein 8
NCBI Organism
Homo sapiens
Background Reference 01
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007) Hwang, E.S., et al. Immunology 106 (4) :464-469 (2002) Hwang, E.S., et al. J. Immunol. 169 (1) :248-253 (2002)
Other Product Names
Zinc finger CCCH domain-containing protein 8, ZC3H8, ZC3HDC8
Tested Applications
WB, Flow
Protein ID
47117585
Physical Properties
Liquid
Curated Selection
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