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SOX3 Antibody

Product Specifications

Background

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency.

NCBI Gene ID

6658

Swiss Prot

P41225

Accession Number

P41225

Host

Rabbit

Reactivity

Human

Immunogen

This SOX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-196 amino acids from the Central region of human SOX3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Zebrafish, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

45 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SOX3

NCBI Official Name

Transcription factor SOX-3

NCBI Organism

Homo sapiens

Background Reference 01

Dateki, S., et al. J. Clin. Endocrinol. Metab. 95 (8) :4043-4047 (2010)

Background Reference 02

Sato, Y., et al. Mol. Cell. Biochem. 337 (1-2), 267-275 (2010) :

Background Reference 03

Mojsin, M., et al. Biochem. J. 425 (1) :107-116 (2010)

Background Reference 04

Bleyl, S.B., et al. Am. J. Med. Genet.143A (23), 2785-2795 (2007) :

Other Product Names

Transcription factor SOX-3, SOX3

Tested Applications

WB

Protein ID

48429228

Physical Properties

Liquid

Frequently Asked Questions

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