GRIN2A Antibody

Product Specifications

Background

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D) . Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

2903

Swiss Prot

Q12879

Accession Number

Q12879

Host

Rabbit

Reactivity

Mouse

Immunogen

This GRIN2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1057-1084 amino acids from the Central region of human GRIN2A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

165 kDa

Fragment

Rabbit Ig

Symbol

GRIN2A

NCBI Official Name

Glutamate receptor ionotropic, NMDA 2A

NCBI Organism

Homo sapiens

Background Reference 01

Endele, S., et al. Nat. Genet. 42 (11) :1021-1026 (2010)

Background Reference 02

Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)

Background Reference 03

Saus, E., et al.Psychiatr Res 44 (14) :971-978 (2010)

Background Reference 04

Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :

Other Product Names

Glutamate receptor ionotropic, NMDA 2A, GluN2A, Glutamate [NMDA] receptor subunit epsilon-1, N-methyl D-aspartate receptor subtype 2A, NMDAR2A, NR2A, hNR2A, GRIN2A, NMDAR2A