CPA6 Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the family of carboxypeptidases, which catalyze the release of C-terminal amino acid, and have functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Polymorphic variants and a reciprocal translocation t (6;8) (q26; q13) involving this gene, have been associated with Duane retraction syndrome.

NCBI Gene ID

57094

Swiss Prot

Q8N4T0

Accession Number

Q8N4T0

Host

Rabbit

Reactivity

Human

Immunogen

This CPA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-315 amino acids from the Central region of human CPA6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CPA6

NCBI Official Name

Carboxypeptidase A6

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care (2010) In press :

Background Reference 02

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 03

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Background Reference 04

Sharif, S.A., et al. Arthritis Rheum. 60 (10) :2902-2912 (2009)

Other Product Names

Carboxypeptidase A6, 3417-, CPA6, CPAH

Tested Applications

Protein ID

85683250

Physical Properties

Liquid

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