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FBXO21 Antibody

Product Specifications

Background

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants.

NCBI Gene ID

23014

Swiss Prot

O94952

Accession Number

O94952

Host

Rabbit

Reactivity

Mouse

Immunogen

This FBXO21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-501 amino acids from the C-terminal region of human FBXO21.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

72 kDa

Fragment

Rabbit Ig

Symbol

FBXO21

NCBI Official Name

F-box only protein 21

NCBI Organism

Homo sapiens

Background Reference 01

Nakayama, M., et al. Genome Res. 12 (11) :1773-1784 (2002)

Background Reference 02

Cenciarelli, C., et al. Curr. Biol. 9 (20) :1177-1179 (1999)

Other Product Names

F-box only protein 21, FBXO21, FBX21, KIAA0875

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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