ADCY2 Antibody

Product Specifications

Background

This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP) . This enzyme is insensitive to Ca (2+) /calmodulin, and is stimulated by the G protein beta and gamma subunit complex.

NCBI Gene ID

108

Swiss Prot

Q08462

Accession Number

Q08462

Host

Rabbit

Reactivity

Human

Immunogen

This ADCY2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 451-481 amino acids from the Central region of human ADCY2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

124 kDa

Fragment

Rabbit Ig

Symbol

ADCY2

NCBI Official Name

Adenylate cyclase type 2

NCBI Organism

Homo sapiens

Background Reference 01

Halls, M.L., et al. EMBO J. 29 (16) :2772-2787 (2010)

Background Reference 02

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 03

Need, A.C., et al. Eur. J. Hum. Genet. 17 (7) :946-957 (2009)

Background Reference 04

Uhl, G.R., et al. Arch. Gen. Psychiatry 65 (6) :683-693 (2008)

Other Product Names

Adenylate cyclase type 2, ATP pyrophosphate-lyase 2, Adenylate cyclase type II, Adenylyl cyclase 2, ADCY2, KIAA1060

Tested Applications

WB, Flow

Protein ID

118572617

Physical Properties

Liquid

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