NR6A1 Antibody

Product Specifications

Background

This gene encodes an orphan nuclear receptor which is a member of the nuclear hormone receptor family. Its expression pattern suggests that it may be involved in neurogenesis and germ cell development. The protein can homodimerize and bind DNA, but in vivo targets have not been identified. The gene expresses at least alternatively spliced transcript variants.

NCBI Gene ID

2649

Swiss Prot

Q15406

Accession Number

Q15406

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This NR6A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of human NR6A1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

54 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NR6A1

NCBI Official Name

Nuclear receptor subfamily 6 group A member 1

NCBI Organism

Homo sapiens

Background Reference 01

Letra, A., et al. Am. J. Med. Genet.152A (7), 1701-1710 (2010) :

Background Reference 02

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 03

Rajkovic, M., et al. J. Biol. Chem. 279 (50) :52493-52499 (2004)

Background Reference 04

Yang, G., et al. Biol. Reprod. 68 (5) :1620-1630 (2003)

Other Product Names

Nuclear receptor subfamily 6 group A member 1, Germ cell nuclear factor, GCNF, hGCNF, Retinoid receptor-related testis-specific receptor, RTR, hRTR, NR6A1, GCNF