HMOX1 Antibody
Product Specifications
Background
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.
NCBI Gene ID
3162
Swiss Prot
P09601
Accession Number
P09601
Host
Rabbit
Reactivity
Human
Immunogen
This HMOX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-204 amino acids from the Central region of human HMOX1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
33 kDa
Fragment
Rabbit Ig
Symbol
HMOX1
NCBI Official Name
Heme oxygenase 1
NCBI Organism
Homo sapiens
Background Reference 01
Wu, M.M., et al. Toxicol. Appl. Pharmacol. 248 (3) :226-233 (2010)
Background Reference 02
Bolisetty, S., et al. J. Am. Soc. Nephrol. 21 (10) :1702-1712 (2010)
Background Reference 03
Bao, W., et al. PLoS ONE (8), E12371 (2010) :
Background Reference 04
Wu, M.M., et al. J. Biomed. Sci. 17, 70 (2010) :
Other Product Names
Heme oxygenase 1, HO-1, HMOX1, HO, HO1
Tested Applications
WB, Flow
Protein ID
123446
Physical Properties
Liquid
Curated Selection
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