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IRF2 Antibody

Product Specifications

Background

IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4. [provided by RefSeq].

NCBI Gene ID

3660

Swiss Prot

P14316

Accession Number

P14316

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This IRF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-255 amino acids from the Central region of human IRF2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

39 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

IRF2

NCBI Official Name

Interferon regulatory factor 2

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Lace, M.J., et al. Virology 399 (2) :270-279 (2010)

Background Reference 03

Masumi, A., et al. Biochem. Biophys. Res. Commun. 391 (4) :1623-1628 (2010)

Background Reference 04

Daley, D., et al. Hum. Genet. 125 (4) :445-459 (2009)

Other Product Names

Interferon regulatory factor 2, IRF-2, IRF2

Tested Applications

WB

Protein ID

20141499

Physical Properties

Liquid

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