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HOXD13 Antibody

Product Specifications

Background

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. Mutations in this particular gene cause synpolydactyly.

NCBI Gene ID

3239

Swiss Prot

P35453

Accession Number

P35453

Host

Rabbit

Reactivity

Mouse

Immunogen

This HOXD13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-230 amino acids from the Central region of human HOXD13.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

36 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

HOXD13

NCBI Official Name

Homeobox protein Hox-D13

NCBI Organism

Homo sapiens

Background Reference 01

Sugie, Y., et al. Brain Dev. 32 (5) :356-361 (2010)

Background Reference 02

Yerges, L.M., et al. J. Bone Miner. Res. 24 (12) :2039-2049 (2009)

Background Reference 03

Salsi, V., et al. Mol. Cell. Biol. 29 (21) :5775-5788 (2009)

Background Reference 04

Cantile, M., et al. Int. J. Cancer 125 (7) :1532-1541 (2009)

Other Product Names

Homeobox protein Hox-D13, Homeobox protein Hox-4I, HOXD13, HOX4I

Tested Applications

WB

Protein ID

223590221

Physical Properties

Liquid

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