THEMIS Antibody

Product Specifications

Background

This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

387357

Swiss Prot

Q8N1K5

Accession Number

Q8N1K5

Host

Rabbit

Reactivity

Mouse

Immunogen

This THEMIS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 559-588 amino acids from the C-terminal region of human THEMIS.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=55-693

Calculated Molecular Weight

73 kDa

Fragment

Rabbit Ig

Symbol

THEMIS

NCBI Official Name

Protein THEMIS

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Dubois, P.C., et al. Nat. Genet. 42 (4) :295-302 (2010)

Background Reference 03

Bhatti, P., et al. Radiat. Res. 173 (2) :214-224 (2010)

Background Reference 04

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Other Product Names

Protein THEMIS, Thymocyte-expressed molecule involved in selection, THEMIS, C6orf190, C6orf207

Tested Applications

WB, IHC-P

Protein ID

150421530

Physical Properties

Liquid

Curated Selection

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